For research use only. Not for therapeutic Use.
<p style=/line-height:25px/>Clidinium bromide (Cat.No:I003275) is an anticholinergic (specifically a muscarinic antagonist) drug, may help symptoms of cramping and abdominal/stomach pain by decreasing stomach acid, and slowing the intestines.</p>
| Catalog Number | I003275 |
| CAS Number | 3485-62-9 |
| Synonyms | Ro 2-3773 |
| Molecular Formula | C22H26NO3 • Br |
| Purity | ≥95% |
| Target | Neuronal Signaling |
| Solubility | 10 mM in DMSO |
| Storage | Store at -20°C |
| IUPAC Name | (1-methyl-1-azoniabicyclo[2.2.2]octan-3-yl) 2-hydroxy-2,2-diphenylacetate;bromide |
| InChI | InChI=1S/C22H26NO3.BrH/c1-23-14-12-17(13-15-23)20(16-23)26-21(24)22(25,18-8-4-2-5-9-18)19-10-6-3-7-11-19;/h2-11,17,20,25H,12-16H2,1H3;1H/q+1;/p-1 |
| InChIKey | GKEGFOKQMZHVOW-UHFFFAOYSA-M |
| SMILES | O=C(C(C1=CC=CC=C1)(O)C2=CC=CC=C2)OC3C[N+]4(C)CCC3CC4.[Br-] |
| Reference | </br>1:Simultaneous Determination of Clidinium Bromide and Chlordiazepoxide in Combined Dosage Forms by High-Performance Liquid Chromatography. Ashour S, Kattan N.J Pharm (Cairo). 2013;2013:417682. doi: 10.1155/2013/417682. Epub 2013 Feb 24. PMID: 26555978 Free PMC Article</br>2:Stability-indicating HPLC method for simultaneous determination of clidinium bromide and chlordiazepoxide in combined dosage forms. Pathak A, Rai P, Rajput SJ.J Chromatogr Sci. 2010 Mar;48(3):235-9. PMID: 20223092 </br>3:Simultaneous determination of chlordiazepoxide and clidinium bromide in pharmaceutical formulations by derivative spectrophotometry. Toral MI, Richter P, Lara N, Jaque P, Soto C, Saavedra M.Int J Pharm. 1999 Oct 28;189(1):67-74. PMID: 10518686 </br>4:The determination of a degradation product in clidinium bromide drug substance by capillary electrophoresis with indirect UV detection. Nickerson B.J Pharm Biomed Anal. 1997 Apr;15(7):965-71. PMID: 9160263 </br>5:Liquid chromatographic determination of clidinium bromide and clidinium bromide-chlordiazepoxide hydrochloride combinations in capsules. Yuen SM, Lehr G.J Assoc Off Anal Chem. 1991 May-Jun;74(3):461-4. PMID: 1874688 </br>6:Effects of magnesium citrate and clidinium bromide on the excretion of activated charcoal in normal subjects. Vuignier BI, Oderda GM, Gorman RL, Klein-Schwartz W, Watson WA.DICP. 1989 Jan;23(1):26-9. PMID: 2718479 </br>7:[Therapy of the irritable colon using a new drug combination (chlordiazepoxide, clidinium bromide, propyphenazone)]. Realini S, Hofstetter JR.Schweiz Rundsch Med Prax. 1973 Dec 4;62(49):1519-20. French. No abstract available. PMID: 4800527 </br>8:[The irritable colon. Significance of a combination of clidinium bromide, chlordiazepoxide and propyphenazone in its therapy]. Thiébaud G.Schweiz Rundsch Med Prax. 1973 Dec 4;62(49):1521-5. French. No abstract available. PMID: 4752182 </br>9:Analysis of premedication for sigmoidoscopy: a comparative study with chlordiazepoxide alone and in combination with clidinium bromide. Ehrlich R.Am J Proctol. 1969 Apr;20(2):130-3. No abstract available. PMID: 5818877 </br>10:[TRANQUILIZING AGENTS IN THE TREATMENT OF GASTRODUODENAL ULCER. (RESULTS OBTAINED WITH THE ASSOCIATION OF AN ANSIOLYTIC: CHLORODIAZEPOXIDE AND AN ANTICHOLINERGIC: CLIDINIUM BROMIDE]. GALANNAVARRO JL.Rev Clin Esp. 1964 Mar 15;92:342-51. Spanish. No abstract available. PMID: 14142206 |
