Clindamycin hydrochloride

• CAT Number: A000180
• CAS Number: 21462-39-5
• Molecular Formula: C₁₈H₃₃ClN₂O₅S · HCl
• Molecular Weight: 461.44
• Purity: 98%
• Target: Bacterial
• Appearance: White solid
• Storage: 3 years -20C powder
• Analysis method: HPLC
• IUPAC Name: (2S,4R)-N-[(1S,2S)-2-chloro-1-[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-methylsulfanyloxan-2-yl]propyl]-1-methyl-4-propylpyrrolidine-2-carboxamide;hydrochloride
• InChI: InChI=1S/C18H33ClN2O5S.ClH/c1-5-6-10-7-11(21(3)8-10)17(25)20-12(9(2)19)16-14(23)13(22)15(24)18(26-16)27-4;/h9-16,18,22-24H,5-8H2,1-4H3,(H,20,25);1H/t9-,10+,11-,12+,13-,14+,15+,16+,18+;/m0./s1
• InChIKey: AUODDLQVRAJAJM-XJQDNNTCSA-N
• SMILES: CCC[C@@H]1C[C@H](N(C1)C)C(=O)N[C@@H]([C@@H]2[C@@H]([C@@H]([C@H]([C@H](O2)SC)O)O)O)[C@H](C)Cl.Cl

Clindamycin hydrochloride（Cat No.:A000180）is an antibiotic commonly used to treat bacterial infections, particularly those caused by Gram-positive organisms. As a lincosamide antibiotic, it works by inhibiting bacterial protein synthesis, thus preventing the growth of bacteria. This compound is effective against a range of infections, including skin and soft tissue infections, respiratory infections, and infections caused by anaerobic bacteria. Clindamycin hydrochloride is often used in the treatment of severe infections where other antibiotics may be less effective or contraindicated. It is available in oral, topical, and injectable forms for clinical use.

Reference

Lovmar, Martin, and Tanel Tenson. /The Mechanism of Action of Macrolides, Lincosamides and Streptogramin B Reveals the Nascent Peptide Exit Path in the Ribosome./Journal of Molecular Microbiology 330.5 (2003): 1005-014.