Clinofibrate

• CAT Number: R047358
• CAS Number: 30299-08-2
• Molecular Formula: C28H36O6
• Molecular Weight: 468.58
• Purity: ≥95%
• Synonyms: 1,1-Bis[4’-(1’’-carboxy-1’’-methylpropoxy)phenyl]cyclohexane; 2,2’-[Cyclohexylidenebis(4,1-phenyleneoxy)]bis[2-methyl-butanoic Acid; Lipoclin; ?S 8527
• Target: HMGCR
• Storage: 3 years -20C powder
• IUPAC Name: 2-[4-[1-[4-(2-carboxybutan-2-yloxy)phenyl]cyclohexyl]phenoxy]-2-methylbutanoic acid
• InChI: InChI=1S/C28H36O6/c1-5-26(3,24(29)30)33-22-14-10-20(11-15-22)28(18-8-7-9-19-28)21-12-16-23(17-13-21)34-27(4,6-2)25(31)32/h10-17H,5-9,18-19H2,1-4H3,(H,29,30)(H,31,32)
• InChIKey: BMOVQUBVGICXQN-UHFFFAOYSA-N
• SMILES: CCC(C)(C(=O)O)OC1=CC=C(C=C1)C2(CCCCC2)C3=CC=C(C=C3)OC(C)(CC)C(=O)O

Clinofibrate（Cat No.:R047358）is a lipid-lowering agent in the fibrate class, primarily used to treat hyperlipidemia by reducing triglycerides and increasing high-density lipoprotein (HDL) levels. It works by activating peroxisome proliferator-activated receptors (PPARs), enhancing lipid metabolism and promoting the clearance of very-low-density lipoproteins (VLDL) from the bloodstream. Clinofibrate is beneficial in managing conditions like atherosclerosis and coronary artery disease, helping to improve cardiovascular health. Its action on lipid profiles makes it a valuable option in treating dyslipidemia, particularly in patients unresponsive to first-line therapies like statins.