CLK1-IN-3

• CAT Number: I041227
• CAS Number: 2922550-28-3
• Molecular Formula: C24H23FN6O
• Molecular Weight: 430.48
• Purity: ≥95%
• Synonyms: N-[3-(5-fluoropyridin-3-yl)-1H-pyrrolo[2,3-b]pyridin-5-yl]-4-(4-methylpiperazin-1-yl)benzamide
• InChI: InChI=1S/C24H23FN6O/c1-30-6-8-31(9-7-30)20-4-2-16(3-5-20)24(32)29-19-11-21-22(15-28-23(21)27-14-19)17-10-18(25)13-26-12-17/h2-5,10-15H,6-9H2,1H3,(H,27,28)(H,29,32)
• InChIKey: LQKHTRXKHPHEPP-UHFFFAOYSA-N
• SMILES: CN1CCN(CC1)C2=CC=C(C=C2)C(=O)NC3=CC4=C(NC=C4C5=CC(=CN=C5)F)N=C3

CLK1-IN-3（Cat No.:I041227）is a small molecule inhibitor that targets CLK1 (CDC-like kinase 1), an enzyme involved in regulating alternative splicing of pre-mRNA. By inhibiting CLK1, this compound can alter splicing patterns, affecting the expression of genes involved in processes such as cell cycle progression, DNA repair, and apoptosis. CLK1-IN-3 is being studied for its potential in cancer research, where dysregulated splicing plays a key role in tumorigenesis. It may also have therapeutic implications in diseases where splicing abnormalities are implicated, offering a novel approach for targeted treatment.