Clopidogrel thiolactone

• CAT Number: I000548
• CAS Number: 1147350-75-1
• Molecular Formula: C16H16ClNO3S
• Molecular Weight: 337.82
• Purity: ≥95%
• Target: GPCR/G Protein
• Solubility: 10 mM in DMSO
• Storage: Store at +4C
• IUPAC Name: methyl (2S)-2-(2-chlorophenyl)-2-(2-oxo-4,6,7,7a-tetrahydrothieno[3,2-c]pyridin-5-yl)acetate
• InChI: InChI=1S/C16H16ClNO3S/c1-21-16(20)15(11-4-2-3-5-12(11)17)18-7-6-13-10(9-18)8-14(19)22-13/h2-5,8,13,15H,6-7,9H2,1H3/t13?,15-/m0/s1
• InChIKey: JBSAZVIMJUOBNB-WUJWULDRSA-N
• SMILES: COC(=O)[C@H](C1=CC=CC=C1Cl)N2CCC3C(=CC(=O)S3)C2

Clopidogrel Thiolactone(CAT: I000548) is a potent prodrug and key intermediate in antiplatelet therapy research. It acts by inhibiting the P2Y12 adenosine diphosphate (ADP) receptor on platelets, preventing platelet aggregation and reducing thrombotic events. As a precursor to the active metabolite of Clopidogrel, it is essential for studies in cardiovascular pharmacology. Its mechanism of irreversible receptor binding highlights its role in enhancing vascular health and mitigating risks associated with acute coronary syndromes. Widely used in drug discovery and therapeutic optimization, Clopidogrel Thiolactone is a valuable tool for advancing research in cardiovascular medicine and exploring novel antithrombotic strategies.