For research use only. Not for therapeutic Use.
Cloprednol(CAT: R054189) is a synthetic glucocorticoid with anti-inflammatory and immunosuppressive properties. Structurally related to prednisolone, Cloprednol is designed to modulate glucocorticoid receptor activity, helping regulate inflammatory responses by suppressing the expression of pro-inflammatory cytokines and mediators. It has been investigated for potential use in treating conditions such as allergic reactions, autoimmune disorders, and inflammation-related diseases. Although not as widely used or approved as other corticosteroids, Cloprednol remains of interest in pharmacological research for exploring structure-activity relationships and developing glucocorticoids with improved efficacy and reduced side effects.
| CAS Number | 5251-34-3 |
| Synonyms | (8S,9S,10R,11S,13S,14S,17R)-6-chloro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-9,11,12,14,15,16-hexahydro-8H-cyclopenta[a]phenanthren-3-one |
| Molecular Formula | C21H25ClO5 |
| Purity | ≥95% |
| IUPAC Name | (8S,9S,10R,11S,13S,14S,17R)-6-chloro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-9,11,12,14,15,16-hexahydro-8H-cyclopenta[a]phenanthren-3-one |
| InChI | InChI=1S/C21H25ClO5/c1-19-5-3-11(24)7-14(19)15(22)8-12-13-4-6-21(27,17(26)10-23)20(13,2)9-16(25)18(12)19/h3,5,7-8,12-13,16,18,23,25,27H,4,6,9-10H2,1-2H3/t12-,13-,16-,18+,19-,20-,21-/m0/s1 |
| InChIKey | YTJIBEDMAQUYSZ-FDNPDPBUSA-N |
| SMILES | C[C@]12C[C@@H]([C@H]3[C@H]([C@@H]1CC[C@@]2(C(=O)CO)O)C=C(C4=CC(=O)C=C[C@]34C)Cl)O |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
