Clorgyline hydrochloride

• CAT Number: I002307
• CAS Number: 17780-75-5
• Molecular Formula: C₁₃H₁₅Cl₂NO • HCl
• Molecular Weight: 308.63
• Purity: ≥95%
• Synonyms: N-[3-(2,4-dichlorophenoxy)propyl]-N-methyl-2-propyn-1-amine, monohydrochloride
• Target: Monoamine Oxidase
• Solubility: DMSO: 20 mg/mL
• Storage: Store at -20°C
• InChI: InChI=1S/C13H15Cl2NO.ClH/c1-3-7-16(2)8-4-9-17-13-6-5-11(14)10-12(13)15;/h1,5-6,10H,4,7-9H2,2H3;1H
• InChIKey: BBAZDLONIUABKI-UHFFFAOYSA-N
• SMILES: CN(CCCOC1=C(C=C(C=C1)Cl)Cl)CC#C.Cl

Clorgiline is an irreversible and selective inhibitor of monoamine oxidase A (MAO-A) that is used in scientific research; structurally related to Pargyline.

Reference

[1]. Murphy DL, et al. Differential trace amine alterations in individuals receiving acetylenic inhibitors of MAO-A (clorgyline) or MAO-B (selegiline and pargyline). Journal of neural transmission. Supplementum 52: 39-48.