For research use only. Not for therapeutic Use.
Clorotepine mesylate(Cat No.:I024991)is a synthetic compound used primarily as a central nervous system (CNS) agent with antipsychotic properties. It acts as a dopamine receptor antagonist, particularly at the D2 receptor, and may also have effects on other neurotransmitter systems, including serotonin and norepinephrine. This makes it useful for managing disorders like schizophrenia and other psychotic conditions. Clorotepine mesylate is thought to help reduce symptoms such as delusions, hallucinations, and cognitive impairment. While it shows promise in clinical use, further studies are needed to fully understand its safety profile and long-term effectiveness.
Catalog Number | I024991 |
CAS Number | 42505-79-3 |
Synonyms | Clorotepine mesylate; Clorotepin methanesulfonate |
Molecular Formula | C20H25ClN2O3S2 |
Purity | 98% |
Solubility | Soluble in DMSO |
Appearance | Solid powder |
Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
IUPAC Name | 1-(3-chloro-5,6-dihydrobenzo[b][1]benzothiepin-5-yl)-4-methylpiperazine;methanesulfonic acid |
InChI | InChI=1S/C19H21ClN2S.CH4O3S/c1-21-8-10-22(11-9-21)17-12-14-4-2-3-5-18(14)23-19-7-6-15(20)13-16(17)19;1-5(2,3)4/h2-7,13,17H,8-12H2,1H3;1H3,(H,2,3,4) |
InChIKey | XQRUOHZMMIUQSB-UHFFFAOYSA-N |
SMILES | CN1CCN(CC1)C2CC3=CC=CC=C3SC4=C2C=C(C=C4)Cl.CS(=O)(=O)O |
Reference | 1: Roth BL, Craigo SC, Choudhary MS, Uluer A, Monsma FJ Jr, Shen Y, Meltzer HY, Sibley DR. Binding of typical and atypical antipsychotic agents to 5-hydroxytryptamine-6 and 5-hydroxytryptamine-7 receptors. J Pharmacol Exp Ther. 1994 Mar;268(3):1403-10. PMID: 7908055. |