For research use only. Not for therapeutic Use.
Cloxacillin Sodium（Cat No.:A000983）is a semi-synthetic, beta-lactam antibiotic belonging to the penicillin class, specifically designed to resist beta-lactamase enzymes produced by certain bacteria. Effective against gram-positive organisms, particularly Staphylococcus aureus, it is commonly used to treat skin, bone, and joint infections, as well as respiratory tract infections. Cloxacillin Sodium works by inhibiting bacterial cell wall synthesis, leading to cell lysis and death. Its stability against beta-lactamases makes it suitable for combating resistant staph infections, making it a reliable option in both hospital and outpatient settings.
| Catalog Number | A000983 |
| CAS Number | 7081-44-9 |
| Synonyms | NA |
| Molecular Formula | C19H19ClN3NaO6S |
| Purity | ≥95% |
| Target | Beta-lactamase |
| Storage | 3 years -20C powder |
| IUPAC Name | sodium;(2S,5R,6R)-6-[[3-(2-chlorophenyl)-5-methyl-1,2-oxazole-4-carbonyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate;hydrate |
| InChI | InChI=1S/C19H18ClN3O5S.Na.H2O/c1-8-11(12(22-28-8)9-6-4-5-7-10(9)20)15(24)21-13-16(25)23-14(18(26)27)19(2,3)29-17(13)23;;/h4-7,13-14,17H,1-3H3,(H,21,24)(H,26,27);;1H2/q;+1;/p-1/t13-,14+,17-;;/m1../s1 |
| InChIKey | KCUWTKOTPIUBRI-VICXVTCVSA-M |
| SMILES | CC1=C(C(=NO1)C2=CC=CC=C2Cl)C(=O)N[C@H]3[C@@H]4N(C3=O)[C@H](C(S4)(C)C)C(=O)[O-].O.[Na+] |
| Reference | <p>Guzmán, Flavio, MD. /Beta Lactams Antibiotics (penicillins and Cephalosporins) Mechanism of Action.” <em>Medical Pharmacology</em>. Pharmacology Corner, 29 Nov. 2008. Web. 21 Aug. 2012.</p><p>Pitout JD, Sanders CC, Sanders WE Jr. Antimicrobial resistance with focus on beta-lactam resistance in gram-negative bacilli. Am J Med 1997; 103:51.</p></span></p> |
