Codeine Phosphate

For research use only. Not for therapeutic Use.

  • CAT Number: I025057
  • CAS Number: 41444-62-6
  • Molecular Formula: C36H50N2O15P2
  • Molecular Weight: 812.74
  • Purity: 98%
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Codeine Phosphate(CAT: I025057) is a naturally occurring opioid analgesic derived from Papaver somniferum. It acts primarily as a partial agonist at the μ-opioid receptor, modulating pain perception by altering nociceptive signaling pathways in the central nervous system. Codeine Phosphate is widely used in research to study opioid receptor pharmacodynamics, pain management, and drug metabolism. Its role as a prodrug, metabolized into morphine via the CYP2D6 pathway, makes it an important model compound for exploring interindividual variability in drug response. This compound is critical in advancing research on opioid pharmacology and the development of safer analgesics.


Catalog Number I025057
CAS Number 41444-62-6
Synonyms

Codeine Phosphate

Molecular Formula C36H50N2O15P2
Purity 98%
Solubility Soluble in DMSO
Appearance Solid powder
Storage Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
IUPAC Name (4R,4aR,7S,7aR,12bS)-9-methoxy-3-methyl-2,4,4a,7,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-ol;phosphoric acid;hydrate
InChI InChI=1S/2C18H21NO3.2H3O4P.H2O/c2*1-19-8-7-18-11-4-5-13(20)17(18)22-16-14(21-2)6-3-10(15(16)18)9-12(11)19;2*1-5(2,3)4;/h2*3-6,11-13,17,20H,7-9H2,1-2H3;2*(H3,1,2,3,4);1H2/t2*11-,12+,13-,17-,18-;;;/m00.../s1
InChIKey DKSZLDSPXIWGFO-BLOJGBSASA-N
SMILES C[N@]1CC[C@]23c4c5ccc(c4O[C@H]2[C@H](C=C[C@H]3[C@H]1C5)O)OC.C[N@]1CC[C@]23c4c5ccc(c4O[C@H]2[C@H](C=C[C@H]3[C@H]1C5)O)OC.O.OP(=O)(O)O.OP(=O)(O)O

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