For research use only. Not for therapeutic Use.
Cofrogliptin（Cat No.:I043414）is a selective, oral inhibitor of the enzyme dipeptidyl peptidase-4 (DPP-4), which plays a role in regulating glucose metabolism. By inhibiting DPP-4, Cofrogliptin increases the levels of active incretin hormones, such as GLP-1 (glucagon-like peptide-1), which enhance insulin secretion and reduce glucagon release in response to meals. This helps lower blood glucose levels, making Cofrogliptin a potential therapeutic option for managing type 2 diabetes. It is often used in combination with other antidiabetic drugs to improve glycemic control in patients with this condition.
| CAS Number | 1844874-26-5 |
| Synonyms | (2R,3S,5R,6S)-2-(2,5-difluorophenyl)-5-(2-methylsulfonyl-4,6-dihydropyrrolo[3,4-c]pyrazol-5-yl)-6-(trifluoromethyl)oxan-3-amine |
| Molecular Formula | C18H19F5N4O3S |
| Purity | ≥95% |
| IUPAC Name | (2R,3S,5R,6S)-2-(2,5-difluorophenyl)-5-(2-methylsulfonyl-4,6-dihydropyrrolo[3,4-c]pyrazol-5-yl)-6-(trifluoromethyl)oxan-3-amine |
| InChI | InChI=1S/C18H19F5N4O3S/c1-31(28,29)27-7-9-6-26(8-14(9)25-27)15-5-13(24)16(30-17(15)18(21,22)23)11-4-10(19)2-3-12(11)20/h2-4,7,13,15-17H,5-6,8,24H2,1H3/t13-,15+,16+,17-/m0/s1 |
| InChIKey | GUBOXFWNNXSQNH-SVGFKBNWSA-N |
| SMILES | CS(=O)(=O)N1C=C2CN(CC2=N1)[C@@H]3C[C@@H]([C@H](O[C@@H]3C(F)(F)F)C4=C(C=CC(=C4)F)F)N |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
