Colistin B Sulfate Salt (~90%)

• CAT Number: C000392
• CAS Number: 1338055-88-1
• Molecular Formula: C₅₂H₉₈N₁₆O₁₃ • x(H₂SO₄)
• Molecular Weight: 1253.51
• Purity: ≥95%
• Synonyms: 1-[(2S)-4-Amino-2-[(6-methyl-1-oxoheptyl)amino]butanoic acid]polymyxin E1 Sulfate Salt; Colistin B Sulfate Salt; Polymyxin E2 Sulfate Salt; 1,4,7,10,13,16,19-Heptaazacyclotricosane Cyclic Peptide deriv. Sulfate Salt; Colistin I Sulfate Salt; N2-(6-Methyl-1-oxoheptyl)-L-2,4-diaminobutanoyl-L-threonyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-D-leucyl-L-leucyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-L-threonine (10?4)-Lactam Sulfate Salt
• Solubility: Methanol (Slightly), Water (Slightly)
• Appearance: White to Off-White Solid
• Storage: -20°C, Hygroscopic
• IUPAC Name: N-[(2S)-4-amino-1-[[(2S,3R)-1-[[(2S)-4-amino-1-oxo-1-[[(3S,6S,9S,12S,15R,18S,21S)-6,9,18-tris(2-aminoethyl)-3-[(1R)-1-hydroxyethyl]-12,15-bis(2-methylpropyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptazacyclotricos-21-yl]amino]butan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-1-oxobutan-2-yl]-6-methylheptanamide;sulfuric acid
• InChI: InChI=1S/C52H98N16O13.H2O4S/c1-27(2)11-9-10-12-40(71)59-32(13-19-53)47(76)68-42(31(8)70)52(81)64-35(16-22-56)44(73)63-37-18-24-58-51(80)41(30(7)69)67-48(77)36(17-23-57)61-43(72)33(14-20-54)62-49(78)38(25-28(3)4)66-50(79)39(26-29(5)6)65-45(74)34(15-21-55)60-46(37)75;1-5(2,3)4/h27-39,41-42,69-70H,9-26,53-57H2,1-8H3,(H,58,80)(H,59,71)(H,60,75)(H,61,72)(H,62,78)(H,63,73)(H,64,81)(H,65,74)(H,66,79)(H,67,77)(H,68,76);(H2,1,2,3,4)/t30-,31-,32+,33+,34+,35+,36+,37+,38+,39-,41+,42+;/m1./s1
• InChIKey: XYXFTCPJFHFTTO-KSPURPISSA-N
• SMILES: C[C@H]([C@H]1C(=O)NCC[C@@H](C(=O)N[C@H](C(=O)N[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N1)CCN)CCN)CC(C)C)CC(C)C)CCN)NC(=O)[C@H](CCN)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCN)NC(=O)CCCCC(C)C)O.OS(=O)(=O)O

Colistin B Sulfate Salt(CAT: C000392) is a polymyxin antibiotic derived from Bacillus polymyxa, widely used in microbiology and pharmaceutical research. It exhibits potent bactericidal activity against Gram-negative bacteria by disrupting bacterial cell membranes. This sulfate salt form ensures high solubility and stability, making it suitable for in vitro and in vivo studies. Colistin B Sulfate Salt is commonly utilized in investigating mechanisms of antimicrobial resistance, such as multidrug-resistant (MDR) pathogens, and in developing novel combination therapies. Its reliable activity and specificity provide researchers with a critical tool for advancing antimicrobial strategies and understanding bacterial pathogenesis.