For research use only. Not for therapeutic Use.
Colistin Sulfate（Cat No.:A000440）is an antibiotic used in the treatment of multidrug-resistant Gram-negative bacterial infections, particularly in cases involving Pseudomonas aeruginosa, Acinetobacter baumannii, and Klebsiella pneumoniae. As a polypeptide antibiotic, it works by disrupting the bacterial cell membrane, leading to leakage of cellular contents and ultimately bacterial death. Colistin Sulfate is primarily used in serious infections when other antibiotics are ineffective. Its application is especially important in treating infections in critically ill patients or those with compromised immune systems. It is available in both oral and intravenous formulations for targeted bacterial infections.
| Catalog Number | A000440 |
| CAS Number | 1264-72-8 |
| Synonyms | Polymixin E Sulfate |
| Molecular Formula | C52H98N16O13 •2.5 H2SO4 (Colistin Sulfate A) |
| Purity | ≥95% |
| Storage | 3 years -20C powder |
| Reference | <p>Falagas, M. E. /Colistin: The Revival of Polymyxins for the Management of Multidrug-resistant Gram-negative Bacterial Infections./ <em>Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America</em> 40.9 (2005): 1333-341. <em>www.ncbi.gov</em>. Web. 10 Sept. 2012.</p>Bergen, Philip J. et. al. /Colistin Methanesulfonate Is an Inactive Prodrug of Colistin against Pseudomonas Aeruginosa./ Antimicrobial Agents and Chemotherapy 50.6 (2006): 1953-958. Ncbi.gov. Web. 5 Oct. 2012.<p>Leifert C., Ritchie J.Y. and Waites W.M., Contaminants of plant-tissue and cell cultures. World Journal of Microbiology and Biotechnology, Vol. 7, pp. 452-469, 1991.</p><p>MJ Mueller, W Brodschelm. /Signaling in the elicitation process is mediated through theoctadecanoid pathway leading to jasmonic acid/. Proc. Natl. Acad. Sci. USAVol. 90, pp. 7490-7494, August 1993.</p></span></p> |
