Columbin

• CAT Number: M010878
• CAS Number: 546-97-4
• Molecular Formula: C20H22O6
• Molecular Weight: 358.39
• Purity: ≥95%
• Synonyms: (1R,4R,4aR,6aR,9S,10aS,10bS)-9-(3-Furanyl)-1,4,4a,5,6,6a,9,10,10a,10b-decahydro-4-hydroxy-4a,10a-dimethyl-1,4-etheno-3H,7H-benzo[1,2-c:3,4-c/’]dipyran-3,7-dione;(1R,4R,4aR,6aR,9S,10aS,10bS)-9-(3-Furanyl)decahydro-4-hydroxy-4a,10a-dimethyl-1,4-etheno-
• Target: Anti-infection
• Storage: -20°C
• IUPAC Name: (1R,2S,3S,5S,8R,11R,12R)-5-(furan-3-yl)-12-hydroxy-3,11-dimethyl-6,14-dioxatetracyclo[10.2.2.02,11.03,8]hexadec-15-ene-7,13-dione
• InChI: 1S/C20H22O6/c1-18-9-14(11-5-8-24-10-11)25-16(21)12(18)3-6-19(2)15(18)13-4-7-20(19,23)17(22)26-13/h4-5,7-8,10,12-15,23H,3,6,9H2,1-2H3/t12-,13+,14-,15-,18+,19+,20-/m0/s1
• InChIKey: AALLCALQGXXWNA-DURQJQQASA-N
• SMILES: CC12CCC3C(=O)OC(CC3(C1C4C=CC2(C(=O)O4)O)C)C5=COC=C5

Columbin(CAT: M010878) is a natural compound found in various plant species, including Columbiana uniflora and Aquilegia vulgaris (also known as columbine). Its mode of action involves being a benzylisoquinoline alkaloid with potential biological activities. Pharmacologically, columbin has been studied for its diverse effects, including antioxidant, antimicrobial, anti-inflammatory, and anticancer properties. It has shown promise in various preclinical studies, demonstrating its potential therapeutic applications in managing oxidative stress, combating microbial infections, reducing inflammation, and exhibiting anticancer effects by inducing apoptosis and inhibiting tumor growth.