Compound 10w

• CAT Number: I047223
• CAS Number: 1336890-05-1
• Molecular Formula: C20H24F2N8O3
• Molecular Weight: 462.45
• Purity: ≥95%
• Storage: 3 years -20°C powder
• SMILES: COC1=C2N=C(C(F)F)[N](C3=NC(=NC(=N3)N4CCOCC4)N5CCOCC5)C2=CC(=C1)N

Compound 10w, a substituted pyrazolo [1,5-a] pyrimidine amide derivative, shows good anticancer activity against HeLa cell line, with IC50 of less than 10 µM against HeLa cell.

Reference

[1] Kumar AKA, et al. Medicinal Chemistry Research. 2017; 26, 714–744.