For research use only. Not for therapeutic Use.
Compound 11, a non-toxic and selective δ-secretase inhibitor (IC50=0.7 μM, in fluorescence-based assay) that interacts with both the active site and allosteric site of δ-secretase in Co-crystal structure analysis. The IC50 value of the compound 11 towards δ-secretase in Pala cells is 0.8 μM.
| Catalog Number | I020970 |
| CAS Number | 842964-18-5 |
| Molecular Formula | C10H12N4O2 |
| Purity | ≥95% |
| Storage | 3 years -20°C powder |
| SMILES | NC1=CC=C(N2CCOCC2)C3=NON=C13 |
| Reference | [1] Zhang Z, et al. Nat Commun. 2017 Mar 27;8:14740. |
