Conivaptan HCl

• CAT Number: A001205
• CAS Number: 168626-94-6
• Molecular Formula: C32H26N4O2.HCl
• Molecular Weight: 535.04
• Purity: ≥95%
• Target: Vasopressin Receptor
• Solubility: >14.8mg/mL in DMSO
• Storage: 3 years -20C powder

Conivaptan HCl is an orally active, non-peptide, vasopressin V1A and V2 receptor antagonist, used in the treatment of euvolemic and hypervolemic hyponatremia.Conivaptan (0.03, 0.1 and 0.3 mg/kg i.v.) dose-dependently increases urine volume and reduces urine osmolality in both myocardial infarction and sham-operated rats. Conivaptan (0.3 mg/kg i.v.) significantly reduces right ventricular systolic pressure, left ventricular end-diastolic pressure, lung/body weight and right atrial pressure in myocardial infarction rats. Conivaptan (0.3 mg/kg i.v.) significantly increases dP/dt(max)/left ventricular pressure in myocardial infarction rats.