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73-03-0-Cordycepin Cordycepin

Cordycepin

For research use only. Not for therapeutic Use.

  •  $385/1 g

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  • CAT Number: R008436
  • CAS Number: 73-03-0
  • Molecular Formula: C10H13N5O3
  • Molecular Weight: 251.24
  • Purity: 97%
  • Lead time: 2 weeks for QC and delivery
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Related Small Molecules: 4-(4-Ethylphenyl)-2-fluoro-1-(4-pentylphenyl)benzene     1-Bromo-2-fluoro-5-nitro-3-(trifluoromethyl)benzene     2-CHLORO-6-METHYLBENZALDEHYDE    

Cordycepin is a versatile chemical building block widely used in organic synthesis, providing essential structural components for pharmaceutical, agrochemical, and material science research. It serves as a key intermediate in the development of complex molecules, enabling the synthesis of bioactive compounds, functional materials, and innovative drug candidates. Researchers and students in organic chemistry and pharmaceutical sciences rely on Cordycepin for its stability, reactivity, and compatibility with various synthetic methodologies, making it an indispensable tool in modern chemical research.


CAS Number 73-03-0
Synonyms

3′-Deoxyadenosine; 9-(3-Deoxy-β-D-ribofuranosyl)adenine; 9-(3-Deoxy-β-D-erythro-pentofuranosyl)-9H-purin-6-amine; 9-Cordyceposidoadenine; Cordycepine; NSC 401022; NSC 63984;

Molecular Formula C10H13N5O3
Purity 97%
Target Anti-infection
Appearance Off-White Solid
Storage -20°C
IUPAC Name (2R,3R,5S)-2-(6-aminopurin-9-yl)-5-(hydroxymethyl)oxolan-3-ol
InChI InChI=1S/C10H13N5O3/c11-8-7-9(13-3-12-8)15(4-14-7)10-6(17)1-5(2-16)18-10/h3-6,10,16-17H,1-2H2,(H2,11,12,13)/t5-,6+,10+/m0/s1
InChIKey OFEZSBMBBKLLBJ-BAJZRUMYSA-N
SMILES C1[C@H](O[C@H]([C@@H]1O)N2C=NC3=C(N=CN=C32)N)CO
Reference

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1:The Protective Effect of Cordycepin on D-Galactosamine/Lipopolysaccharide-Induced Acute Liver Injury. Li J, Zhong L, Zhu H, Wang F.Mediators Inflamm. 2017;2017:3946706. doi: 10.1155/2017/3946706. Epub 2017 Mar 28. PMID: 28522898<br />
2:Characterization of Newly Bred <i>Cordyceps militaris</i> Strains for Higher Production of Cordycepin through HPLC and URP-PCR Analysis. Lee HH, Kang N, Park I, Park J, Kim I, Kim J, Kim N, Lee JY, Seo YS.J Microbiol Biotechnol. 2017 Apr 25. doi: 10.4014/jmb.1701.01043. [Epub ahead of print] PMID: 28438013 Free Article<br />
3:Development of High Cordycepin-Producing <i>Cordyceps militaris</i> Strains. Kang N, Lee HH, Park I, Seo YS.Mycobiology. 2017 Mar;45(1):31-38. doi: 10.5941/MYCO.2017.45.1.31. Epub 2017 Mar 31. PMID: 28435352 Free PMC Article<br />
4:Metronomic Cordycepin Therapy Prolongs Survival of Oral Cancer-Bearing Mice and Inhibits Epithelial-Mesenchymal Transition. Su NW, Wu SH, Chi CW, Liu CJ, Tsai TH, Chen YJ.Molecules. 2017 Apr 13;22(4). pii: E629. doi: 10.3390/molecules22040629. PMID: 28406456 Free Article<br />
5:Protective Effect of Cordycepin on Experimental Testicular Ischemia/Reperfusion Injury in Rats. Okur MH, Arslan S, Aydogdu B, Zeytun H, Basuguy E, Arslan MS, Ibiloglu I, Kaplan I.J Invest Surg. 2017 Apr 12:1-8. doi: 10.1080/08941939.2016.1246629. [Epub ahead of print] PMID: 28402715<br />
6:Cordycepin confers neuroprotection in mice models of intracerebral hemorrhage via suppressing NLRP3 inflammasome activation. Cheng Y, Wei Y, Yang W, Song Y, Shang H, Cai Y, Wu Z, Zhao W.Metab Brain Dis. 2017 Apr 11. doi: 10.1007/s11011-017-0003-7. [Epub ahead of print] PMID: 28401330<br />
7:Cordycepin induces human lung cancer cell apoptosis by inhibiting nitric oxide mediated ERK/Slug signaling pathway. Hwang JH, Park SJ, Ko WG, Kang SM, Lee DB, Bang J, Park BJ, Wee CB, Kim DJ, Jang IS, Ko JH.Am J Cancer Res. 2017 Mar 1;7(3):417-432. eCollection 2017. PMID: 28401001 Free PMC Article<br />
8:Cordycepin-enriched WIB-801C from Cordyceps militaris improves functional recovery by attenuating blood-spinal cord barrier disruption after spinal cord injury. Lee JY, Choi HY, Baik HH, Ju BG, Kim WK, Yune TY.J Ethnopharmacol. 2017 May 5;203:90-100. doi: 10.1016/j.jep.2017.03.047. Epub 2017 Mar 30. PMID: 28363523<br />
9:Cordycepin negatively modulates lipopolysaccharide-induced cytokine production by up-regulation of heme oxygenase-1. Qing R, Huang Z, Tang Y, Xiang Q, Yang F.Int Immunopharmacol. 2017 Mar 25;47:20-27. doi: 10.1016/j.intimp.2017.03.002. [Epub ahead of print] PMID: 28351780<br />
10:Cordycepin disrupts leukemia association with mesenchymal stromal cells and eliminates leukemia stem cell activity. Liang SM, Lu YJ, Ko BS, Jan YJ, Shyue SK, Yet SF, Liou JY.Sci Rep. 2017 Mar 7;7:43930. doi: 10.1038/srep43930. PMID: 28266575 Free PMC Article
Research Areas: Cancer Disease Research     Cancer Immunotherapy     Cancer Metabolism Metastasis     Cancer Targeted Therapy    

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