Coronastat(NK01-63)

• CAT Number: I047224
• CAS Number: 2922281-15-8
• Molecular Formula: C22H29F3N3NaO8S
• Molecular Weight: 575.53
• Purity: ≥95%
• Storage: 3 years -20°C powder
• SMILES: CC(C)CC(NC(=O)OCC1=CC(=CC=C1)C(F)(F)F)C(=O)NC(CC2CCNC2=O)C(O)[S](=O)(=O)O[Na]

Coronastat(NK01-63) is a potent inhibitor of the SARS-CoV-2 3CL protease, which is a critical drug target for small molecule COVID-19, given its likely druggability and essentiality in the viral maturation and replication cycle.

Reference

[1] Liu H, et al. Nat Commun. 2022 Apr 7;13(1):1891.