Corticosterone 21-Acetate

• CAT Number: R053020
• CAS Number: 1173-26-8
• Molecular Formula: C23H32O5
• Molecular Weight: 388.504
• Purity: ≥95%
• Synonyms: Cort A; NSC 81764; SKF 5654; (11β)-21-(Acetyloxy)-11-hydroxy-pregn-4-ene-3,20-dione
• Storage: -20°C
• IUPAC Name: [2-[(8S,9S,10R,11S,13S,14S,17S)-11-hydroxy-10,13-dimethyl-3-oxo-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate
• InChI: InChI=1S/C23H32O5/c1-13(24)28-12-20(27)18-7-6-17-16-5-4-14-10-15(25)8-9-22(14,2)21(16)19(26)11-23(17,18)3/h10,16-19,21,26H,4-9,11-12H2,1-3H3/t16-,17-,18+,19-,21+,22-,23-/m0/s1
• InChIKey: WKQCPUMQBMFPLC-ZWFCQKKLSA-N
• SMILES: CC(=O)OCC(=O)C1CCC2C1(CC(C3C2CCC4=CC(=O)CCC34C)O)C

Corticosterone 21-Acetate is a synthetic derivative of corticosterone, a glucocorticoid hormone involved in stress response, metabolism, and immune regulation. In this derivative, an acetate group is attached at the 21st position, enhancing its stability and bioavailability. This compound is commonly used in research to study the effects of corticosteroids on various physiological processes, including inflammation and immune function. Researchers also explore its potential therapeutic applications in treating conditions related to adrenal insufficiency, inflammation, and other disorders influenced by glucocorticoid activity.