Corticosterone

For research use only. Not for therapeutic Use.

  • CAT Number: I003769
  • CAS Number: 50-22-6
  • Molecular Formula: C21H30O4
  • Molecular Weight: 346.50
  • Purity: ≥95%
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Corticosterone(Cat No.:I003769)is a steroid hormone produced by the adrenal cortex in response to stress, playing a crucial role in regulating the body’s response to stress and maintaining homeostasis. It is a key glucocorticoid in many vertebrates, including rodents, and is involved in processes such as metabolism, immune response, and inflammation. In humans, its counterpart is cortisol. Corticosterone helps regulate blood sugar levels, blood pressure, and immune function. It is often studied in animal models of stress, as it can provide insights into the hormonal regulation of stress responses and related disorders.


Catalog Number I003769
CAS Number 50-22-6
Synonyms

(8S,9S,10R,11S,13S,14S,17S)-11-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3(2H)-one

Molecular Formula C21H30O4
Purity ≥95%
Target Vitamin D Related/Nuclear Receptor
Solubility 10 mM in DMSO
Storage Store at RT
IUPAC Name (8S,9S,10R,11S,13S,14S,17S)-11-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one
InChI InChI=1S/C21H30O4/c1-20-8-7-13(23)9-12(20)3-4-14-15-5-6-16(18(25)11-22)21(15,2)10-17(24)19(14)20/h9,14-17,19,22,24H,3-8,10-11H2,1-2H3/t14-,15-,16+,17-,19+,20-,21-/m0/s1
InChIKey OMFXVFTZEKFJBZ-HJTSIMOOSA-N
SMILES C[C@]12CCC(=O)C=C1CC[C@@H]3[C@@H]2[C@H](C[C@]4([C@H]3CC[C@@H]4C(=O)CO)C)O
Reference

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<br>[1]. Gasser PJ, et al. Corticosterone-sensitive monoamine transport in the rat dorsomedial hypothalamus: potential role for organiccation transporter 3 in stress-induced modulation of monoaminergic neurotransmission. J Neurosci. 2006 Aug 23;26(34):8758-8766.
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