Corticotropin-releasing factor human

• CAT Number: I005223
• CAS Number: 86784-80-7
• Molecular Formula: C208H344N60O63S2
• Molecular Weight: 4757.45
• Purity: ≥95%
• Target: Non-selective CRF
• Solubility: DMSO
• Storage: Store at -20℃

Corticotropin-releasing factor human (Cat.No:I005223) is a neuropeptide involved in the regulation of the body’s stress response. It plays a crucial role in coordinating various physiological and behavioral reactions to stressors. Research suggests that targeting this factor may hold therapeutic potential for conditions associated with dysregulated stress responses, such as anxiety and depression.

Reference

[1]. Kaneko T et al. Activation of adenylate cyclase-cyclic AMP-protein kinase A signaling by corticotropin-releasing factorwithin the dorsolateral bed nucleus of the stria terminalis is involved in pain-induced aversion. Eur J Neurosci. 2016 Sep 30.

[2]. Bangasser DA et al. Corticotropin-releasing factor overexpression gives rise to sex differences in Alzheimer/’s disease-related signaling. Mol Psychiatry. 2016 Oct 18.

[3]. Tenk J et al. Acute central effects of corticotropin-releasing factor (CRF) on energy balance: Effects of age and gender. Peptides. 2016 Nov;85:63-72.