Cortisone-d8

• CAT Number: S000834
• Molecular Formula: C21H20D8O5
• Molecular Weight: 368.49
• Purity: ≥95%
• Target: Vitamin D Related/Nuclear Receptor
• IUPAC Name: (8S,9S,10R,13S,14S,17R)-2,2,4,6,6,9,12,12-octadeuterio-17-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-1,7,8,14,15,16-hexahydrocyclopenta[a]phenanthrene-3,11-dione
• InChI: InChI=1S/C21H28O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h9,14-15,18,22,26H,3-8,10-11H2,1-2H3/t14-,15-,18+,19-,20-,21-/m0/s1/i3D2,5D2,9D,10D2,18D
• InChIKey: MFYSYFVPBJMHGN-BMUVRMCQSA-N
• SMILES: CC12CCC(=O)C=C1CCC3C2C(=O)CC4(C3CCC4(C(=O)CO)O)C

Cortisone-d8（Cat No.:S000834） is a deuterated form of cortisone, where eight hydrogen atoms are replaced with deuterium, resulting in the molecular formula C21H20D8O5. This stable isotope-labeled compound is used extensively in mass spectrometry and nuclear magnetic resonance (NMR) spectroscopy to enhance analytical precision in studies of cortisone’s metabolism and pharmacokinetics. Cortisone-d8 serves as an invaluable tool in endocrinology research, helping to elucidate the mechanisms of cortisone action in inflammation and immune response. It is particularly useful for developing improved therapeutic strategies for conditions like arthritis, allergies, and autoimmune diseases.