Corylin

• CAT Number: I003976
• CAS Number: 53947-92-5
• Molecular Formula: C20H16O4
• Molecular Weight: 320.34
• Purity: ≥95%
• Target: Stem Cell/Wnt
• Solubility: 10 mM in DMSO
• Storage: Store at -20°C
• IUPAC Name: 3-(2,2-dimethylchromen-6-yl)-7-hydroxychromen-4-one
• InChI: InChI=1S/C20H16O4/c1-20(2)8-7-13-9-12(3-6-17(13)24-20)16-11-23-18-10-14(21)4-5-15(18)19(16)22/h3-11,21H,1-2H3
• InChIKey: PWAACAMQKVIVPZ-UHFFFAOYSA-N
• SMILES: CC1(C=CC2=C(O1)C=CC(=C2)C3=COC4=C(C3=O)C=CC(=C4)O)C

Corylin（Cat No.:I003976）is a naturally occurring flavonoid found in several plants, including Sophora flavescens. It exhibits a range of bioactivities, including antioxidant, anti-inflammatory, and anti-cancer effects. Corylin has been studied for its potential to modulate various signaling pathways, such as NF-κB and MAPK/ERK, which are involved in inflammation and cell survival. This flavonoid also shows promise in regulating cellular processes like apoptosis and cell proliferation. As a bioactive compound, Corylin holds potential for therapeutic applications, especially in managing chronic inflammatory diseases and certain cancers.

Reference

[1]. Lee SW, et al. Phenolic compounds isolated from Psoralea corylifolia inhibit IL-6-induced STAT3 activation. Planta Med. 2012 Jun;78(9):903-6.