Corynoxine B

• CAT Number: I002267
• CAS Number: 17391-18-3
• Molecular Formula: C22H28N2O4
• Molecular Weight: 384.47
• Purity: ≥95%
• Synonyms: methyl (E)-2-[(3R,6’S,7’S,8’aS)-6′-ethyl-2-oxospiro[1H-indole-3,1′-3,5,6,7,8,8a-hexahydro-2H-indolizine]-7′-yl]-3-methoxyprop-2-enoate
• IUPAC Name: methyl (E)-2-[(3R,6'S,7'S,8'aS)-6'-ethyl-2-oxospiro[1H-indole-3,1'-3,5,6,7,8,8a-hexahydro-2H-indolizine]-7'-yl]-3-methoxyprop-2-enoate
• InChI: InChI=1S/C22H28N2O4/c1-4-14-12-24-10-9-22(17-7-5-6-8-18(17)23-21(22)26)19(24)11-15(14)16(13-27-2)20(25)28-3/h5-8,13-15,19H,4,9-12H2,1-3H3,(H,23,26)/b16-13+/t14-,15+,19+,22-/m1/s1
• InChIKey: DAXYUDFNWXHGBE-XYEDMTIPSA-N
• SMILES: CCC1CN2CCC3(C2CC1C(=COC)C(=O)OC)C4=CC=CC=C4NC3=O

Corynoxine B（Cat No.:I002267) is an autophagy enhancer derived from the Uncaria rhynchophylla plant, traditionally used in Chinese medicine. It promotes the clearance of damaged cells and proteins by stimulating autophagy, a cellular degradation process. Corynoxine B shows promise in neuroprotection and the treatment of neurodegenerative diseases such as Parkinson’s and Alzheimer’s, where impaired autophagy contributes to disease progression. Additionally, its anti-inflammatory and antioxidant properties support overall cellular health. As a natural compound with multiple therapeutic potentials, Corynoxine B is a valuable candidate for research in neurodegenerative and age-related diseases.