COTI-2

For research use only. Not for therapeutic Use.

  • CAT Number: I006193
  • CAS Number: 1039455-84-9
  • Molecular Formula: C19H22N6S
  • Molecular Weight: 366.50
  • Purity: ≥95%
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COTI-2 (Cat.No:I006193) is an investigational anticancer drug with promising potential. It targets mutant p53, a common genetic alteration in various cancers, to restore normal function and inhibit tumor growth. Preclinical studies have shown encouraging results, highlighting COTI-2 as a potential therapeutic option for patients with p53-mutated cancers. Clinical trials are underway to evaluate its efficacy and safety in humans.


Catalog Number I006193
CAS Number 1039455-84-9
Synonyms

COTI-2; COTI2; COTI 2;(E)-N/’-(6,7-dihydroquinolin-8(5H)-ylidene)-4-(pyridin-2-yl)piperazine-1-carbothiohydrazide

Molecular Formula C19H22N6S
Purity ≥95%
Target MDM-2/p53
Solubility Soluble in DMSO
Storage Store at -20°C
IUPAC Name N-(6,7-dihydro-5H-quinolin-8-ylideneamino)-4-pyridin-2-ylpiperazine-1-carbothioamide
InChI InChI=1S/C19H22N6S/c26-19(23-22-16-7-3-5-15-6-4-10-21-18(15)16)25-13-11-24(12-14-25)17-8-1-2-9-20-17/h1-2,4,6,8-10H,3,5,7,11-14H2,(H,23,26)/b22-16+
InChIKey UTDAKQMBNSHJJB-JWGURIENSA-N
SMILES S=C(N/N=C1C(N=CC=C2)=C2CCC1)N(CC3)CCN3C4=NC=CC=C4

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