For research use only. Not for therapeutic Use.
Coumarin 6H, a Coumarin (Coumarin (HY-N0709)) derivative, is a laser dye. The fluorescence emission of Coumarin 6H can be enhanced by hydrogen bonding interactions[1][2].
The Coumarin 6H with twistblocked and stronger electron-donating julolidine group exhibits higher quantum yield, better biocompatibility, as well as less background fluorescence when suppressed by a fluorescence quenching group. Thus, the Coumarin 6H in probe LH-1 may help to reduce the background fluorescence. In probe LH-1, the fluorescence of Coumarin 6H fluorophore not only can be quenched by the rotation of N-N group, but also can be quenched by the 2,4-dinitrobenzenze group via donor-excited photoinduced electron transfer (d-PET) mechanism[2].
| Catalog Number | I030593 |
| CAS Number | 58336-35-9 |
| Synonyms | 3-oxa-13-azatetracyclo[7.7.1.02,7.013,17]heptadeca-1,5,7,9(17)-tetraen-4-one |
| Molecular Formula | C15H15NO2 |
| Purity | ≥95% |
| InChI | InChI=1S/C15H15NO2/c17-13-6-5-11-9-10-3-1-7-16-8-2-4-12(14(10)16)15(11)18-13/h5-6,9H,1-4,7-8H2 |
| InChIKey | MZSOXGPKUOAXNY-UHFFFAOYSA-N |
| SMILES | C1CC2=C3C(=C4C(=C2)C=CC(=O)O4)CCCN3C1 |
| Reference | [1]. P M French, et al. Passively mode-locked cw Coumarin 6 ring dye laser. Opt Lett. 1989 Feb 15;14(4):217-8. [2]. Zhixiang Han, et al. A novel fluorescent probe with extremely low background fluorescence for sensing hypochlorite in zebrafish. Anal Biochem. 2020 Aug 1;602:113795. |
