For research use only. Not for therapeutic Use.
CP-20961 is a potent synthetic non-immunogenic adjuvant that induces arthritis[1][2].
CP-20961 can be used in animal modeling to construct animal arthritis models.Avridine-induced arthritis is severe and long lasting in LEW and DA rats[2].
CP-20961 (10 mg/kg, i.v., once either 24, 48, or 72 hours post-burn) had no effect on survival after challenge with P. aeruginosa 96 hours post-burn[3].
| Catalog Number | R053497 |
| CAS Number | 35607-20-6 |
| Synonyms | 2-[3-(dioctadecylamino)propyl-(2-hydroxyethyl)amino]ethanol |
| Molecular Formula | C43H90N2O2 |
| Purity | ≥95% |
| InChI | InChI=1S/C43H90N2O2/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-36-44(38-35-39-45(40-42-46)41-43-47)37-34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h46-47H,3-43H2,1-2H3 |
| InChIKey | WXNRAKRZUCLRBP-UHFFFAOYSA-N |
| SMILES | CCCCCCCCCCCCCCCCCCN(CCCCCCCCCCCCCCCCCC)CCCN(CCO)CCO |
| Reference | [1]. Brun JG, et al. Effects of calprotectin in avridine-induced arthritis. APMIS. 1995 Mar;103(3):233-40. [2]. Vingsbo C, et al. Avridine-induced arthritis in rats; a T cell-dependent chronic disease influenced both by MHC genes and by non-MHC genes. Clin Exp Immunol. 1995 Mar;99(3):359-63. [3]. Stinnett JD, et al. Synthetic immunomodulators for prevention of fatal infections in a burned guinea pig model. Ann Surg. 1983 Jul;198(1):53-7. |
