CP-22185

• CAT Number: I006203
• CAS Number: 52758-03-9
• Molecular Formula: C17H19N
• Molecular Weight: 237.35
• Purity: ≥95%
• Synonyms: CP-22185; CP22185; CP 22185; Sertraline hydrochloride specified impurity B [EP]; UNII-X4CR040L3W.;(1RS,4RS)-N-Methyl-4-phenyl-1,2,3,4-tetrahydronaphthalen-1-amine
• Solubility: Soluble in DMSO, not in water
• Storage: 0 - 4°C for short term ,or -20 °C for long term
• IUPAC Name: (1R,4R)-N-methyl-4-phenyl-1,2,3,4-tetrahydronaphthalen-1-amine
• InChI: InChI=1S/C17H19N/c1-18-17-12-11-14(13-7-3-2-4-8-13)15-9-5-6-10-16(15)17/h2-10,14,17-18H,11-12H2,1H3/t14-,17-/m1/s1
• InChIKey: NVXPZMLRGBVYQV-RHSMWYFYSA-N
• SMILES: CNC1CCC(C2=CC=CC=C12)C3=CC=CC=C3

CP-22185(CAT: I006203) is a selective and potent antagonist of the prostaglandin D2 (PGD2) receptor DP1, which plays a key role in allergic responses and inflammation. By blocking the DP1 receptor, CP-22185 is being studied for its ability to reduce symptoms of allergic conditions such as asthma and allergic rhinitis. Its mechanism of action involves inhibiting the effects of PGD2, thereby preventing vasodilation, bronchoconstriction, and the recruitment of inflammatory cells. This compound is valuable in research exploring the therapeutic potential of DP1 receptor antagonism for treating inflammatory and allergic disorders, offering insights into novel anti-inflammatory strategies.