CP 31398 dihydrochloride

• CAT Number: I010664
• CAS Number: 1217195-61-3
• Molecular Formula: C22H26N4O.HCl
• Molecular Weight: 435.39
• Purity: ≥95%
• Synonyms: N/’-[2-[2-(4-Methoxyphenyl)ethenyl]-4-quinazolinyl]-N,N-dimethyl-1,3-propanediamine dihydrochloride
• Target: MDM-2/p53
• Solubility: Soluble to 100 mM in water and to 100 mM in DMSO
• Storage: Desiccate at RT
• IUPAC Name: N-[2-[(E)-2-(4-methoxyphenyl)ethenyl]quinazolin-4-yl]-N',N'-dimethylpropane-1,3-diamine;dihydrochloride
• InChI: InChI=1S/C22H26N4O.2ClH/c1-26(2)16-6-15-23-22-19-7-4-5-8-20(19)24-21(25-22)14-11-17-9-12-18(27-3)13-10-17;;/h4-5,7-14H,6,15-16H2,1-3H3,(H,23,24,25);2*1H/b14-11+
• InChIKey: WWIFDJIOGCGSBS-IVKCLRODSA-N
• SMILES: CN(C)CCCNC1=NC(=NC2=CC=CC=C21)/C=C/C3=CC=C(C=C3)OC.Cl.Cl

CP 31398 dihydrochloride（Cat No.:I010664）is a synthetic small molecule that functions as a stabilizer of the p53 tumor suppressor protein. It works by enhancing the stability and activity of mutant p53, a protein frequently mutated in various cancers. By restoring the function of p53, CP 31398 dihydrochloride promotes cell cycle arrest and apoptosis in cancer cells, potentially slowing tumor growth. It has shown promise in preclinical studies for treating cancers with p53 mutations, including breast, lung, and colon cancers. Ongoing research is focused on evaluating its clinical efficacy and safety as an anticancer agent.