For research use only. Not for therapeutic Use.
CP-320626(Cat No.:I006208)is a selective and potent inhibitor of the enzyme dipeptidyl peptidase IV (DPP-IV), which plays a crucial role in the breakdown of incretin hormones such as GLP-1 and GIP. By inhibiting DPP-IV, CP-320626 increases the levels of these hormones, leading to enhanced insulin secretion and improved blood glucose control. It has been studied for its potential use in treating type 2 diabetes mellitus by improving glycemic control. Research is ongoing to assess its efficacy, safety, and long-term benefits compared to other DPP-IV inhibitors currently available in the market.
Catalog Number | I006208 |
CAS Number | 186430-23-9 |
Synonyms | CP-320626; CP320626; CP 320626; UNII-WHL1Z3GN15.;1H-Indole-2-carboxamide, 5-chloro-N-((1S)-1-((4-fluorophenyl)methyl)-2-(4-hydroxy-1-piperidinyl)-2-oxoethyl)- |
Molecular Formula | C23H23ClFN3O3 |
Purity | ≥95% |
Target | LGPa Inhibitor |
Solubility | Soluble in DMSO, not in water |
Storage | 0 - 4°C for short term ,or -20 °C for long term |
IUPAC Name | 5-chloro-N-[(2S)-3-(4-fluorophenyl)-1-(4-hydroxypiperidin-1-yl)-1-oxopropan-2-yl]-1H-indole-2-carboxamide |
InChI | InChI=1S/C23H23ClFN3O3/c24-16-3-6-19-15(12-16)13-20(26-19)22(30)27-21(11-14-1-4-17(25)5-2-14)23(31)28-9-7-18(29)8-10-28/h1-6,12-13,18,21,26,29H,7-11H2,(H,27,30)/t21-/m0/s1 |
InChIKey | YDCGVASFVACWKF-NRFANRHFSA-N |
SMILES | C1CN(CCC1O)C(=O)[C@H](CC2=CC=C(C=C2)F)NC(=O)C3=CC4=C(N3)C=CC(=C4)Cl |