For research use only. Not for therapeutic Use.
CP-447697 is a lipophilic C5a receptor antagonist with an IC50 value of 31 nM. CP-447697 can be used for the research of inflammation[1].
| Catalog Number | I042675 |
| CAS Number | 1092847-21-6 |
| Synonyms | 4-[1-benzothiophene-3-carbonyl-[2-(4-chlorophenyl)ethyl]amino]-N-(2,4-difluorophenyl)piperidine-1-carboxamide |
| Molecular Formula | C29H26ClF2N3O2S |
| Purity | ≥95% |
| InChI | InChI=1S/C29H26ClF2N3O2S/c30-20-7-5-19(6-8-20)11-16-35(28(36)24-18-38-27-4-2-1-3-23(24)27)22-12-14-34(15-13-22)29(37)33-26-10-9-21(31)17-25(26)32/h1-10,17-18,22H,11-16H2,(H,33,37) |
| InChIKey | UMERSEDFPNHLEN-UHFFFAOYSA-N |
| SMILES | C1CN(CCC1N(CCC2=CC=C(C=C2)Cl)C(=O)C3=CSC4=CC=CC=C43)C(=O)NC5=C(C=C(C=C5)F)F |
| Reference | [1]. Blagg J, et al. Small, non-peptide C5a receptor antagonists: part 1. Bioorg Med Chem Lett. 2008 Oct 15;18(20):5601-4. |
