For research use only. Not for therapeutic Use.
A potent and subtype selective GABAA receptor partial agonist potentially useful in treating generalized anxiety disorder; the Mdr1 P-glycoprotein (P-gp) substrate
| Catalog Number | I047548 |
| CAS Number | 1259477-42-3 |
| Molecular Formula | C20H24FN3O3.CH4O3S |
| Purity | ≥95% |
| IUPAC Name | N-[3-fluoro-4-[2-(propylamino)ethoxy]phenyl]-4-oxo-1,5,6,7-tetrahydroindole-3-carboxamide;methanesulfonic acid |
| InChI | InChI=1S/C20H24FN3O3.CH4O3S/c1-2-8-22-9-10-27-18-7-6-13(11-15(18)21)24-20(26)14-12-23-16-4-3-5-17(25)19(14)16;1-5(2,3)4/h6-7,11-12,22-23H,2-5,8-10H2,1H3,(H,24,26);1H3,(H,2,3,4) |
| SMILES | CCCNCCOC1=C(C=C(C=C1)NC(=O)C2=CNC3=C2C(=O)CCC3)F.CS(=O)(=O)O |
| Reference | CL Shaffer et al. Metabolism and disposition of a g-aminobutyric acid type A receptor partial agonist in humans. Drug Metab. Disp. (2008), 36(4), 655-662.
K Venkatakrishnan et al. Central nervous system pharmacokinetics of the Mdr1 P-glycoprotein substrate CP-615,003. Drug Metab. Disp. (2007), 35(8), 1341-1349 |
