CP21R7

• CAT Number: I001003
• CAS Number: 125314-13-8
• Molecular Formula: C₁₉H₁₅N₃O₂
• Molecular Weight: 317.35
• Purity: ≥95%
• Synonyms: 3-(3-aminophenyl)-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione
• Target: Stem Cell/Wnt
• Solubility: DMSO: ≥ 34 mg/mL
• Storage: Store at -20°C
• IUPAC Name: 3-(3-aminophenyl)-4-(1-methylindol-3-yl)pyrrole-2,5-dione
• InChI: InChI=1S/C19H15N3O2/c1-22-10-14(13-7-2-3-8-15(13)22)17-16(18(23)21-19(17)24)11-5-4-6-12(20)9-11/h2-10H,20H2,1H3,(H,21,23,24)
• InChIKey: RGTAEYDIDMGJLX-UHFFFAOYSA-N
• SMILES: CN1C=C(C2=CC=CC=C21)C3=C(C(=O)NC3=O)C4=CC(=CC=C4)N

CP21R7(CAT: I001003) is a potent and selective inhibitor of Glycogen Synthase Kinase-3 Beta (GSK-3β), a serine/threonine kinase involved in regulating various cellular processes, including cell proliferation, apoptosis, and metabolism. By inhibiting GSK-3β, CP21R7 modulates key signaling pathways such as the Wnt/β-catenin and PI3K/Akt pathways, which are often dysregulated in diseases like cancer, neurodegenerative disorders, and diabetes. Its high selectivity makes it a valuable compound in oncology and neurological research, providing insights into therapeutic strategies for conditions driven by abnormal GSK-3β activity, including Alzheimer’s disease, bipolar disorder, and tumor progression.