CPI-169

• CAT Number: I001746
• CAS Number: 1450655-76-1
• Molecular Formula: C27H36N4O5S
• Molecular Weight: 528.66
• Purity: ≥95%
• Storage: 3 years-20°Cpowder
• SMILES: CCS(=O)(=O)N1CCC(CC1)C(C)N2C(=C(C3=CC=CC=C32)C(=O)NCC4=C(C=C(NC4=O)C)OC)C

CPI-169 is a potent, and selective EZH2 inhibitor with IC50 of 0.24 nM, 0.51 nM, and 6.1 nM for EZH2 WT, EZH2 Y641N, and EZH1, respectively.

Reference

[1] Bradley WD, et al. Chem Biol. 2014, 21(11), 1463-1475.