CPI-360

• CAT Number: I002345
• CAS Number: 1802175-06-9
• Molecular Formula: C25H31N3O4
• Molecular Weight: 437.53
• Purity: ≥95%
• Storage: 3 years-20°Cpowder
• SMILES: CC1=CC(=C(C(=O)N1)CNC(=O)C2=C(N(C3=CC=CC=C32)C(C)C4CCOCC4)C)OC

CPI-360 is a potent, selective,and SAM-competitive EZH1 inhibitor with IC50 of 102.3 nM, >100-fold selectivity over other methyltransferases.

Reference

[1] Bradley WD, et al. Chem Biol. 2014, 21(11), 1463-1475.