CPTH2

• CAT Number: R039520
• CAS Number: 357649-93-5
• Molecular Formula: C14H14ClN3S
• Molecular Weight: 291.79
• Purity: ≥95%
• Synonyms: 2-[4-(4-Chlorophenyl)-2-thiazolyl]hydrazone-cyclopentanone; 4-(4-Chlorophenyl)-2(3H)-thiazolone-cyclopentylidenehydrazone
• Target: Apoptosis
• Storage: Store at -20°C
• IUPAC Name: 4-(4-chlorophenyl)-N-(cyclopentylideneamino)-1,3-thiazol-2-amine
• InChI: InChI=1S/C14H14ClN3S/c15-11-7-5-10(6-8-11)13-9-19-14(16-13)18-17-12-3-1-2-4-12/h5-9H,1-4H2,(H,16,18)
• InChIKey: YYTHPXHGWSAKIZ-UHFFFAOYSA-N
• SMILES: C1CCC(=NNC2=NC(=CS2)C3=CC=C(C=C3)Cl)C1

CPTH2（Cat No.:R039520）is a selective inhibitor of the protein arginine methyltransferase PRMT5, which plays a critical role in regulating gene expression and various cellular processes through the methylation of arginine residues in proteins. By inhibiting PRMT5, CPTH2 disrupts oncogenic signaling pathways and has shown potential in preclinical studies for its anti-cancer properties, particularly in hematologic malignancies and solid tumors with aberrant PRMT5 activity. This compound’s ability to modulate epigenetic regulation highlights its promise as a therapeutic agent, offering new strategies for targeting cancer and other diseases linked to dysregulated methylation processes.