For research use only. Not for therapeutic Use.
CR-1-30-B is an inactive enantiomer of CR-1-31-B. CR-1-30-B, as a control, is inactive against eIF4A and has no apparent effect on the induction of MUC1-C translation[1].
| Catalog Number | I044494 |
| CAS Number | 1352914-53-4 |
| Synonyms | (1S,2S,3R,3aS,8bR)-1,8b-dihydroxy-N,6,8-trimethoxy-3a-(4-methoxyphenyl)-3-phenyl-2,3-dihydro-1H-cyclopenta[b][1]benzofuran-2-carboxamide |
| Molecular Formula | C28H29NO8 |
| Purity | ≥95% |
| InChI | InChI=1S/C28H29NO8/c1-33-18-12-10-17(11-13-18)28-23(16-8-6-5-7-9-16)22(26(31)29-36-4)25(30)27(28,32)24-20(35-3)14-19(34-2)15-21(24)37-28/h5-15,22-23,25,30,32H,1-4H3,(H,29,31)/t22-,23-,25-,27+,28+/m0/s1 |
| InChIKey | KLSIFOJPWJBRFH-DFEWDZLZSA-N |
| SMILES | COC1=CC=C(C=C1)C23C(C(C(C2(C4=C(O3)C=C(C=C4OC)OC)O)O)C(=O)NOC)C5=CC=CC=C5 |
| Reference | [1]. Jin C, et al. Targeting the eIF4A RNA helicase blocks translation of the MUC1-C oncoprotein [published correction appears in Oncogene. 2021 May;40(18):3347]. Oncogene. 2013;32(17):2179-2188. |
