For research use only. Not for therapeutic Use.
CrBKA is a fluorogenic small-molecule substrate of SIRT6 with weak activity[1].
| Catalog Number | I041306 |
| CAS Number | 2260810-48-6 |
| Synonyms | benzyl N-[(2S)-6-[[(E)-but-2-enoyl]amino]-1-[(4-methyl-2-oxochromen-7-yl)amino]-1-oxohexan-2-yl]carbamate |
| Molecular Formula | C28H31N3O6 |
| Purity | ≥95% |
| InChI | InChI=1S/C28H31N3O6/c1-3-9-25(32)29-15-8-7-12-23(31-28(35)36-18-20-10-5-4-6-11-20)27(34)30-21-13-14-22-19(2)16-26(33)37-24(22)17-21/h3-6,9-11,13-14,16-17,23H,7-8,12,15,18H2,1-2H3,(H,29,32)(H,30,34)(H,31,35)/b9-3+/t23-/m0/s1 |
| InChIKey | MZNAVDKTIVTYMY-BSQRELMASA-N |
| SMILES | CC=CC(=O)NCCCCC(C(=O)NC1=CC2=C(C=C1)C(=CC(=O)O2)C)NC(=O)OCC3=CC=CC=C3 |
| Reference | [1]. Wang H L, et al. Interactions between sirtuins and fluorogenic small-molecule substrates offer insights into inhibitor design. Rsc Advances, 2017, 7(58): 36214-36222. |
