For research use only. Not for therapeutic Use.
CRCD2 is an NT5C2 (cytosolic 5’ nucleotidase II) inhibitor with a kd of 70.9 μM. It enhances the cytotoxic effects of 6-MP and effectively reverses thiopurine resistance mediated by genetic and non-genetic mechanisms of NT5C2 activation in ALL.
| Catalog Number | I047228 |
| Molecular Formula | C17H16N4O2S |
| Purity | ≥95% |
| Reference | [1] Reglero C, et al. Cancer Discov. 2022;12(11):2646-2665. |
