Creatine-d3

For research use only. Not for therapeutic Use.

  • CAT Number: I041509
  • CAS Number: 143827-19-4
  • Molecular Formula: C4H6D3N3O2
  • Molecular Weight: 134.15
  • Purity: ≥95%
Inquiry Now

Creatine-d3 is the deuterium labeled Creatine[1]. Creatine, an endogenous amino acid derivative, plays an important role in cellular energy, especially in muscle and brain[2].
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].


Catalog Number I041509
CAS Number 143827-19-4
Synonyms

2-[carbamimidoyl(trideuteriomethyl)amino]acetic acid

Molecular Formula C4H6D3N3O2
Purity ≥95%
InChI InChI=1S/C4H9N3O2/c1-7(4(5)6)2-3(8)9/h2H2,1H3,(H3,5,6)(H,8,9)/i1D3
InChIKey CVSVTCORWBXHQV-FIBGUPNXSA-N
SMILES CN(CC(=O)O)C(=N)N
Reference

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.
 [Content Brief]

[2]. Nouioua S, et al. Creatine deficiency syndrome. A treatable myopathy due to arginine-glycine amidinotransferase (AGAT) deficiency. Neuromuscul Disord. 2013 Aug;23(8):670-4.
 [Content Brief]

Request a Quote