Creatinolfosfate

• CAT Number: I025191
• CAS Number: 6903-79-3
• Molecular Formula: C4H12N3O4P
• Molecular Weight: 197.13
• Purity: 98%
• Synonyms: Nergize; Creatinolfosfate, Creatinol Phosphate; creatinol-O-phosphate
• Solubility: Soluble in DMSO
• Appearance: Solid powder
• Storage: -20°C
• IUPAC Name: 1-(2-Hydroxyethyl)-1-methylguanidine dihydrogen phosphate (ester)
• InChI: InChI=1S/C4H12N3O4P/c1-7(4(5)6)2-3-11-12(8,9)10/h2-3H2,1H3,(H3,5,6)(H2,8,9,10)
• InChIKey: FOIPWTMKYXWFGC-UHFFFAOYSA-N
• SMILES: NC(N(CCOP(O)(O)=O)C)=N

Creatinolfosfate（Cat No.:I025191）, also known as Creatinol Phosphate or creational-O-phosphate, is a biochemical compound that has been studied for its potential effects on heart contractility. It is a derivative of creatine, a naturally occurring substance involved in energy metabolism. Creatinolfosfate is believed to enhance cardiac performance by increasing the availability of adenosine triphosphate (ATP), the primary energy source for heart muscle contraction.

Reference

1: Godfraind T, Saleh MM. Action of creatinol-O-phosphate on the contractility changes evoked by hypoxia and ischemia in rat isolated heart. Arzneimittelforschung. 1984;34(9):968-72. PubMed PMID: 6542374.
2: Ferrini R, Miragoli G. Protective effect of creatinol O-phosphate (COP) on some experimental arrhythmias in vitro and in vivo. Arzneimittelforschung. 1979;29(9a):1475-7. PubMed PMID: 575497.
3: Godfraind T, Ghysel-Burton J, Merlo L. The action of creatinol 0-phosphate on the inotropic effect of isoprenaline in isolated rat atria and in anesthetized dogs. Arzneimittelforschung. 1979;29(9a):1465-7. PubMed PMID: 575493.
4: Marzo A, Ghirardi P. Pharmacological and toxicological properties of creatinol O-phosphate. A review. Arzneimittelforschung. 1979;29(9a):1449-52. Review. PubMed PMID: 395957.