CREBtide TFA

• CAT Number: I040203
• Molecular Formula: C73H129N29O19.xC2HF3O2
• Molecular Weight: 1716.99 (free acid)
• Purity: ≥95%

CREBtide TFA  (Cat No.: I040203) is a synthetic peptide that mimics the activator protein (CREB) pathway, which plays a crucial role in regulating gene expression in response to various signals, such as hormones and neurotransmitters. By activating CREB, CREBtide TFA can enhance memory formation, neuroplasticity, and cellular survival, making it useful in studying cognitive functions and neurodegenerative diseases. This compound is typically used in research to explore the molecular mechanisms behind learning, memory, and neuronal resilience, offering insights into potential therapeutic strategies.

Reference

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[2]. Colbran JL, et al. cAMP-dependent protein kinase, but not the cGMP-dependent enzyme, rapidly phosphorylates delta-CREB, and a synthetic delta-CREB peptide. Biochem Cell Biol. 1992 Oct-Nov;70(10-11):1277-82.
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[3]. Harum KH, et al. Cognitive impairment in Coffin-Lowry syndrome correlates with reduced RSK2 activation. Neurology. 2001 Jan 23;56(2):207-14.
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