For research use only. Not for therapeutic Use.
CSF1R-IN-12（Cat No.:I043659）is a selective inhibitor of the colony-stimulating factor 1 receptor (CSF1R), a key regulator of monocyte and macrophage development. This compound has shown potential in targeting various inflammatory diseases, including cancer and autoimmune conditions, by modulating the tumor microenvironment. CSF1R-IN-12 works by inhibiting CSF1R signaling, thereby reducing macrophage recruitment and activation. Its specificity for CSF1R provides a promising therapeutic approach, minimizing off-target effects. Research into CSF1R-IN-12 continues to explore its efficacy in clinical applications related to chronic inflammation and immune modulation.
| CAS Number | 2361556-35-4 |
| Synonyms | 4-[4-methyl-6-[[6-(trifluoromethyl)pyridin-3-yl]methylamino]pyridin-3-yl]-2,3-dihydroisoindol-1-one |
| Molecular Formula | C21H17F3N4O |
| Purity | ≥95% |
| IUPAC Name | 4-[4-methyl-6-[[6-(trifluoromethyl)pyridin-3-yl]methylamino]pyridin-3-yl]-2,3-dihydroisoindol-1-one |
| InChI | InChI=1S/C21H17F3N4O/c1-12-7-19(26-9-13-5-6-18(25-8-13)21(22,23)24)27-10-16(12)14-3-2-4-15-17(14)11-28-20(15)29/h2-8,10H,9,11H2,1H3,(H,26,27)(H,28,29) |
| InChIKey | NUASBLXKMUYBJO-UHFFFAOYSA-N |
| SMILES | CC1=CC(=NC=C1C2=C3CNC(=O)C3=CC=C2)NCC4=CN=C(C=C4)C(F)(F)F |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
