CTP Synthetase-IN-1

• CAT Number: I042281
• CAS Number: 2338811-71-3
• Molecular Formula: C20H19F3N6O3S2
• Molecular Weight: 512.53
• Purity: ≥95%
• Synonyms: 2-[2-(cyclopropylsulfonylamino)-1,3-thiazol-4-yl]-2-methyl-N-[5-[6-(trifluoromethyl)pyrazin-2-yl]pyridin-2-yl]propanamide
• InChI: InChI=1S/C20H19F3N6O3S2/c1-19(2,15-10-33-18(27-15)29-34(31,32)12-4-5-12)17(30)28-16-6-3-11(7-25-16)13-8-24-9-14(26-13)20(21,22)23/h3,6-10,12H,4-5H2,1-2H3,(H,27,29)(H,25,28,30)
• InChIKey: CZIDGRDZSFIUHX-UHFFFAOYSA-N
• SMILES: CC(C)(C1=CSC(=N1)NS(=O)(=O)C2CC2)C(=O)NC3=NC=C(C=C3)C4=CN=CC(=N4)C(F)(F)F

CTP Synthetase-IN-1（Cat No.:I042281）is a small molecule inhibitor targeting CTP synthetase (CTPS), an enzyme involved in the synthesis of cytidine triphosphate (CTP), a nucleotide essential for DNA and RNA synthesis. CTPS plays a critical role in regulating cellular metabolism and proliferation. By inhibiting CTPS, CTP Synthetase-IN-1 aims to disrupt nucleotide metabolism, leading to reduced cell growth and proliferation, especially in rapidly dividing cancer cells. This compound has potential as an anticancer agent, particularly in cancers that rely on high nucleotide synthesis for tumor growth and survival, showing promise in preclinical studies.