Cu-ATSM

• CAT Number: R065449
• CAS Number: 68341-09-3
• Molecular Formula: C8H14CuN6S2
• Molecular Weight: 321.91
• Purity: ≥95%
• Synonyms: copper-ATSM;CuII(atsm)
• Storage: -20°C
• IUPAC Name: copper;N/'-methyl-N-[(E)-[(3E)-3-[(N-methyl-C-sulfidocarbonimidoyl)hydrazinylidene]butan-2-ylidene]amino]carbamimidothioate
• InChI: InChI=1S/C8H16N6S2.Cu/c1-5(11-13-7(15)9-3)6(2)12-14-8(16)10-4;/h1-4H3,(H2,9,13,15)(H2,10,14,16);/q;+2/p-2/b11-5+,12-6+
• InChIKey: SBHDKYTVDCRMOE-JPAPVDFESA-L
• SMILES: CC(=NNC(=NC)[S-])C(=NNC(=NC)[S-])C.[Cu+2]

Cu-ATSM (Copper(II)-diacetyl-bis(N4-methylthiosemicarbazone)) (Cat No.: R065449) is a copper-based radiopharmaceutical compound used in imaging and therapy, particularly for cancer. It acts as a hypoxia-selective agent, selectively accumulating in hypoxic (low-oxygen) tumor tissues, making it useful for imaging tumors with positron emission tomography (PET) or single-photon emission computed tomography (SPECT). Cu-ATSM is also explored for its potential in targeted radiation therapy, as the copper isotope can deliver cytotoxic radiation to hypoxic tumor cells. Research continues to assess its clinical applications and effectiveness.