For research use only. Not for therapeutic Use.
CU CPT 22(cas# 1416324-85-0) is a selective toll-like receptor 1/2 (TLR1/2) inhibitor (IC<sub>50</sub> = 0.58 <span>μ</span>M), exhibits no activity at TLR2/TLR6, TLR3, TLR4 and TLR7 or a panel of 10 representative kinases. <span>CU CPT 22 i</span>nhibits the release of proinflammatory cytokines TNF-<span>α</span> and IL-1<span>β</span>.
| Catalog Number | I011049 |
| CAS Number | 1416324-85-0 |
| Synonyms | CU CPT 22; 3,4,6-Trihydroxy-2-methoxy-5-oxo-5H-benzocycloheptene-8-carboxylic acid hexyl ester |
| Molecular Formula | C19H22O7 |
| Purity | ≥95% |
| Target | Toll-like Receptor (TLR) |
| InChI | 1S/C19H22O7/c1-3-4-5-6-7-26-19(24)12-8-11-10-14(25-2)17(22)18(23)15(11)16(21)13(20)9-12/h8-10,22-23H,3-7H2,1-2H3,(H,20,21) |
| InChIKey | UBQFTTUFRSSOHE-UHFFFAOYSA-N |
| SMILES | CCCCCCOC(C(C=C1C=C(OC)C(O)=C(O)C1=C2O)=CC2=O)=O |
