Cucurbitacin B

• CAT Number: I004339
• CAS Number: 6199-67-3
• Molecular Formula: C32H46O8
• Molecular Weight: 558.70
• Purity: ≥95%
• Synonyms: Cuc B;NSC 49451;NSC 144154
• Target: Autophagy
• Solubility: 10 mM in DMSO
• Storage: Keep in dark place,Sealed in dry,2-8°C
• IUPAC Name: [(E,6R)-6-[(2S,8S,9R,10R,13R,14S,16R,17R)-2,16-dihydroxy-4,4,9,13,14-pentamethyl-3,11-dioxo-2,7,8,10,12,15,16,17-octahydro-1H-cyclopenta[a]phenanthren-17-yl]-6-hydroxy-2-methyl-5-oxohept-3-en-2-yl] acetate
• InChI: InChI=1S/C32H46O8/c1-17(33)40-27(2,3)13-12-23(36)32(9,39)25-21(35)15-29(6)22-11-10-18-19(14-20(34)26(38)28(18,4)5)31(22,8)24(37)16-30(25,29)7/h10,12-13,19-22,25,34-35,39H,11,14-16H2,1-9H3/b13-12+/t19-,20+,21-,22+,25+,29+,30-,31+,32+/m1/s1
• InChIKey: IXQKXEUSCPEQRD-DKRGWESNSA-N
• SMILES: CC(=O)OC(C)(C)C=CC(=O)C(C)(C1C(CC2(C1(CC(=O)C3(C2CC=C4C3CC(C(=O)C4(C)C)O)C)C)C)O)O

Cucurbitacin B（Cat No.:I004339） is a tetracyclic triterpenoid compound derived from the fruit stem of the Cucurbitaceae Melon. It possesses various therapeutic properties, including heat-clearing, detoxifying, and inhibiting liver fibrosis. Cucurbitacin B exhibits effects in reversing cellular immune deficiency, stimulating cellular immune function, preventing hepatic fatty degeneration, and inhibiting liver fibrosis. It can help alleviate symptoms such as jaundice, reduce serum alanine aminotransferase levels, and improve protein metabolism. Clinically, it is used for the treatment of chronic persistent hepatitis and shows promise as a therapeutic option for liver-related disorders.