For research use only. Not for therapeutic Use.
Cucurbitacin D is an active component in Cucurbita texana, disrupts interactions between Hsp90 and two co-chaperones, Cdc37 and p23. Cucurbitacin D prevents Hsp90 client (Her2, Raf, Cdk6, pAkt) maturation without induction of the heat shock response. Anti-cancer activity[1].
| Catalog Number | I018560 |
| CAS Number | 3877-86-9 |
| Molecular Formula | C₃₀H₄₄O₇ |
| Purity | ≥95% |
| Reference | [1]. Hall JA, et al. Cucurbitacin D Is a Disruptor of the HSP90 Chaperone Machinery. J Nat Prod. 2015 Apr 24;78(4):873-9. |
