For research use only. Not for therapeutic Use.
Cu(II)-Elesclomol is a Cu2+ complex of Elesclomol (HY-12040). Cu(II)-Elesclomol induces cuproptosis. Cu(II)-Elesclomol also inducesapoptosis, causes a G1 cell cycle block and induces DNA double strand breaks in K562 cells. Cu(II)-Elesclomol also weakly inhibits DNA topoisomerase I. Cu(II)-Elesclomol has anticancer activity[1].
| Catalog Number | I040560 |
| CAS Number | 1224195-72-5 |
| Molecular Formula | C19H18CuN4O2S2 |
| Purity | ≥95% |
| Reference | [1]. Brian B Hasinoff, et al. Cellular mechanisms of the cytotoxicity of the anticancer drug elesclomol and its complex with Cu(II). hem Pharmacol. 2015 Feb 1;93(3):266-76. [2]. Brian B Hasinoff, et al. Cellular mechanisms of the cytotoxicity of the anticancer drug elesclomol and its complex with Cu(II). hem Pharmacol. 2015 Feb 1;93(3):266-76. |
